Building the Healthcare Brain 
HIP One
Clinical Reasoning
- CMS WISeR · MAC JL
- Live in 30+ clinical use cases
- Processing PA for 1M+ members
- 35+ agents in production
Forward-deployed · Outcome-committed · Live with CMS
Live
Live
Three platforms.One Healthcare Brain.
Production-grade agentic AI for healthcare, delivered by forward-deployed engineers and proven in CMS production. Three platforms — clinical reasoning, patient engagement, ethical governance — running with 50+ enterprise clients and 1M+ Medicare beneficiaries in New Jersey. Genzeon Platforms provides Healthcare Forward Deployed Engineer (FDE) services from the US and India, deploying the Healthcare Brain directly into payer, provider, and federal-program workflows. Claude-First methodology, multi-model architecture.
Live
PES One
Patient Engagement
- 43% avg · 64% peak containment
- 10+ Large Health Systems live
- Patient Engagement & Experience
CPS One
Governance · Compliance
- Zero ONC fines among live clients
- Privacy & Compliance Automation
- AI Readiness & Risk Assessments
- 96% retention · 76% NPS
Security & Compliance
ISO 27001
SOC 2 Type II
HIPAA
50+
Enterprise clients
<3 min
PA decision latency
100%
CMS three-day TAT
12
Patents filed
These numbers meet the operational floor CMS-0057-F sets for affected payers — public quarterly PA-performance reporting (effective March 31, 2026), 7-day standard / 72-hour expedited decision windows, and the January 2027 FHIR Prior Authorization API mandate. HIP One's <3-min median latency on the auto-affirm path delivers turnaround orders of magnitude inside those windows, with the audit lineage that public reporting requires.
Don’t need a full platform? Five HIP One agents — eligibility, pre-check, duplicate request, intake, auto approval — are available individually on Microsoft Marketplace. See the agents catalog →
Just launched · May 2026 · Microsoft Azure Marketplace
HIP One Medical Necessity Agent is live on Microsoft Marketplace.
HIP One Medical Necessity Agent is the production agent that automates payer prior authorization clinical review — the same medical necessity reasoning live in CMS Medicare via the WISeR Innovation Model. Now buyable on Microsoft Azure Marketplace by health plans, Medicare Advantage organizations, and Commercial payers, with full Microsoft Azure billing.
Production proof: CMS Medicare live since January 2026 · 100% CMS 3-day TAT · 12,609 Q1 PA cases · zero auto-denials
Three platforms · one foundation
Built for the decisions that bend healthcare's cost curve.
Healthcare's most expensive decisions aren't taken in EHRs — they're taken in prior authorization queues, contact-center call legs, and privacy incident logs. Genzeon Platforms automates all three.
Health Intelligence Platform
Unify clinical, operational, and financial workflows for utilization management, prior authorization, medical review, and quality measurement on a single AI-native platform. Deployable across every shape (sovereign, government cloud, commercial cloud, on-prem) and consumable as a full platform or as individual agents.
Explore HIP One
Patient Engagement Solutions
Deploy NLU-powered conversational AI across voice, digital, and mobile. Automate patient and member interactions with clinical-grade intelligence that resolves — not just routes. 10 health systems in production.
Explore PES One
CompliancePro Solutions
The privacy and AI-governance platform — the guardrails layer for AI in healthcare. Automate the privacy program lifecycle and operationalize AI Readiness, AI Risk, and AI policy enforcement. Built by privacy professionals for privacy professionals. 96% three-year retention.
Explore CPS OneHow we deliver
Forward-deployed engineering for healthcare AI.
Genzeon Platforms doesn't ship software and disappear. Our engineers embed with payer and provider customers — owning agentic AI deployment, customization, and production operations end-to-end. Outcome-committed engagements. CMS-grade production. Trust earned through accountability, not slideware.
01 · ENGINEERS, EMBEDDED
Named team. End-to-end.
Production engineers embedded with the customer through go-live and steady state. Named clinical reviewers, named platform owners. Accountability traceable to people, not just SLAs.
02 · OUTCOMES, NOT EFFORT
Paid against measured results.
Throughput, accuracy, member satisfaction, savings — whatever can be measured. Outcome-committed contracts mean the engagement model is aligned with what the customer is buying. Not slideware. Not retainer hours.
03 · PRODUCTION, FROM DAY ONE
Live ops, not pilot theater.
CMS WISeR went live January 1, 2026 — the date CMS published, no soft launch. The forward-deployed engineering model means production accountability from go-live, not after a 12-month pilot phase.
CMS WISeR is the proof. 12,609 prior authorization cases processed in Q1 2026 at 100% three-day TAT compliance and zero auto-denials — not because we sold a platform license, but because our engineers own the operational outcome alongside the customer. The forward-deployed engineering model — pioneered by Palantir, validated at scale by Anthropic — has been the way Genzeon Platforms has delivered healthcare agentic AI from day one.
Production scale
Real production. Real numbers. Real customers.
1M+
MEDICARE BENEFICIARIES SERVED
Across CMS WISeR and adjacent prior-auth deployments.
50+
ENTERPRISE CLIENTS
Payers, providers, and government health programs in production.
100%
CMS THREE-DAY TAT
Compliance sustained across 12,609 Q1 2026 prior auth cases.
0
ONC FINES ON RECORD
Across all 50+ enterprise clients in regulated industries.
The brain underneath
Aether One™ — the substrate underneath the Healthcare Brain.
The same patent-protected agent architecture powers HIP One's PA decisions and PES One's conversation resolution — specialized agents, deterministic guardrails, audit-grade traceability. Protected by 12 patents filed and more in preparation. CPS One sits alongside as the privacy and AI-governance counterweight — the guard at the gate when AI enters the workflow.
CMS-validated
Live in real Medicare
The AI-native platform unifying prior authorization, utilization management, medical review, payment integrity, and quality measurement. Available across all deployment environments (sovereign, government cloud, commercial cloud, on premises) and every consumption requirement (full platform, outcome-based, or individual agents). Live in production with Medicare today.
Patent-protected
An IP moat, not a wrapper
Aether One™'s agentic architecture coordinates specialized AI agents across clinical and administrative workflows — with deterministic guardrails and human-in-the-loop validation. A growing patent portfolio — 12 patents filed and more in preparation — protects the method, not just the model weights.
Sovereign-ready
Runs where your data lives
Deploy on-premise, in government clouds, or commercial clouds. Cloud-only competitors can't serve government health programs or high-security payer environments. We can.
Healthcare-native
Not adapted, born here
Every model, workflow, and integration is built from healthcare data and expertise. NLP trained on real clinical records. Interoperability that speaks FHIR, X12, HL7, HETS, PECOS, and esMD natively.
Who we help
Three audiences. One platform. Distinct outcomes.
Health plans replace fragmented PA stacks. Health systems automate millions of patient touchpoints. Government programs get sovereign-deployable AI. Same Aether One™, three buyer journeys.
Payers
Health plans
Automate PA decisions, streamline medical review, meet CMS-0057-F requirements, and reduce delegated UM dependency. Replace incumbent stacks with a CMS-validated platform.
See payer solutions ProvidersHealth systems
Transform patient engagement, automate communications, digitize medical records, and improve quality measures. Voice + digital + mobile across the entire care journey.
See provider solutions GovernmentFederal & state programs
Purpose-built for Medicare FFS prior authorization at the MAC level. The platform deploys where your governance requires (sovereign, government cloud, commercial cloud, on-prem) and is consumed how you need it (full platform, outcome-based, or individual agents). CMS-validated through live production deployment with Novitas Solutions in New Jersey under the WISeR Model.
Learn about WISeRWhat our customers say
Named customers. Privacy-sensitive workflows. Production deployments.
Privacy officers and clinical leaders don't hand out endorsements lightly. A small sample of named customer voices.
"CompliancePro is a tremendous timesaver to keep every busy Privacy Professional organized."
"Our privacy team is enjoying the new assessment tool, which has streamlined our auditing process, allowing us to provide immediate results and feedback to management."
"The reports and graphs are very customizable and user-friendly."
"PES One is a complete ecosystem — not a collection of disconnected tools. It considers the full patient journey and intelligently balances automation with human interaction. The adaptability of the experience was the number one differentiator for our health system."
CompliancePro is the legacy product name for what is now CPS One.
Industry recognition · Ecosystem presence
Recognized for the work. Active in the rooms where healthcare decides.
Two 2026 industry awards mapped to production deployments — not marketing claims. Active membership and presence at the associations where healthcare CIOs, compliance officers, HIM leaders, and quality teams learn, evaluate, and decide.
2026 Awards
Two industry awards. Production work behind both.
Recognition spans the live CMS WISeR deployment, the on-prem AI medical review platform, the agentic prior authorization rollout for DME, and the platform architecture that powers Genzeon Platforms end-to-end.
MEDTECH BREAKTHROUGH · 2026
AI-powered Healthcare Innovation
For the platform behind HIP One — AI medical review, WISeR, and agentic PA.
THE STEVIES · AMERICAN BUSINESS AWARDS · 2026
AI in Healthcare Achievement
For the agentic platform architecture across HIP, PES, and CPS One. Bronze Stevie® alongside Navina, NextGen Healthcare, PayZen, and Ultrasound AI in the 2026 healthcare AI category.
See the full recognition →
Active in the ecosystem
Where healthcare buyers learn, we’re in the room.
Active membership, sponsorship, and speaking presence at the associations that shape healthcare information, compliance, and quality. Not logos on a slide — sessions delivered, booths run, working groups joined.
CHIME
College of Healthcare Information Management Executives. The CIO body for U.S. health systems.
HIMSS
Healthcare Information & Management Systems Society. Featured in the Microsoft Innovation Theater at HIMSS 2026.
AHIMA
American Health Information Management Association. The HIM and clinical-data integrity body.
HCCA
Health Care Compliance Association. Active sponsor and session presenter at HCCA 2026.
NJHA
New Jersey Hospital Association. The Medicare and managed-care convening body in the WISeR deployment market.
Three ways to buy
Platform. Outcomes. Agents.
Most enterprise AI vendors give you one purchase shape: a platform license. Genzeon Platforms sells the way healthcare actually buys — a full platform, a risk-shared outcome, or a single agent that drops into the workflow you already have.
Motion 1
Platform
Full HIP One, PES One, or CPS One license — typically $1.0–2.5M ACV. The bundled experience: orchestration, agents, integrations, and shared infrastructure. The right fit when you're replacing an incumbent stack.
How platform engagements work Motion 2
Outcomes
Risk-shared, performance-based engagements where Genzeon Platforms is paid against measured outcomes — throughput, accuracy, member satisfaction, savings. Available for any line of business where outcomes can be measured. Currently live in Medicare via the CMS WISeR Model.
See a live deployment Motion 3 · new
Agents
Buy one agent, not a platform. Prior Auth Eligibility · Pre-Check · Duplicate Request · Intake · Auto Approval — five HIP One agents available individually as standalone SKUs on Microsoft Azure Marketplace, with additional marketplaces in onboarding.
Each agent inherits from HIP One’s per-criterion citation chains and clinician-in-the-loop architecture. Drops into your existing workflow in days, not quarters.
LIVE ON MICROSOFT MARKETPLACE
See the 5 agents available individually Regulatory catalysts
The market isn't asking for AI — it's mandating it.
| Mandate | What it requires | Genzeon Platforms status |
|---|---|---|
| CMS-0057-F | FHIR PA APIs (CRD/DTR/PAS) by January 1, 2027 — public metrics due March 31, 2026 | Compliant in production |
| CMS WISeR Model | Six-state Medicare FFS prior auth pilot, 2026–2031 | Live · MAC JL (NJ) · Novitas |
| CMS-0062-P | HIPAA FHIR adoption, NCPDP SCRIPT dual channel for PA-RX | PA-RX patent filed |
| CMS ACCESS Model | 10-year outcome-aligned payment, July 2026 – June 2036 | PES One alignment in progress |
| HIPAA Security Rule | 2026 tightening, breach notification | Built-in via CPS One |
| State gold-carding | Dynamic provider cohort management, auto-approval | HIP One module |
Get in touch
Ready to see Genzeon Platforms on your workflow?
A 45-minute walkthrough with our product team. We'll bring live demo environments running on real clinical guidelines and rule packs; you bring the use case you want to test.
Case study
How a federal innovation model met production reality in 90 days.
A long-form report on the first 90 days of the CMS WISeR Model in New Jersey. 12,609 PA cases. 100% three-day TAT. Sub-1-day turnaround for 90% of standard cases by April 2026.
From the newsletter · New on healthcarebrain.ai
Building the Healthcare Brain.
Monthly field notes from inside production healthcare AI. Written by Harsh Singh from inside the WISeR Innovation Model deployment. First Tuesday of every month.
Issue №001 · May 2026
The Talent. Who builds the Brain. Who operates it.
The hidden architecture of who actually ships healthcare AI in production. Engineers, clinical operators, regulatory leads — and why generic AI talent doesn't survive contact with a CMS-grade deployment.
Read the issue on healthcarebrain.ai ↗
Issue №002 · Coming June 2026
Subscribe to receive issue №002 in your inbox.
Monthly cadence. Free. Operator-class readers only — payer CIOs, federal program leads, AI leadership at large health systems, healthcare AI investors. No selling. Unsubscribe in one click.
Subscribe at healthcarebrain.ai ↗The published bar · Healthcare Brain Academy
The minimum knowledge bar for the team Building the Healthcare Brain.
Every Genzeon Platforms FDE has completed Builders Tracks 1–4 before customer engagement. Every customer-facing team member has completed Client Engagement Tracks 1–4 before discovery. Real CPT codes, real CMS regulations, real workflows — the curriculum is published so buyers can verify and candidates can prepare.
A
Academy
From the research hub · New in May 2026
Two technical whitepapers.
Published together: the architectural argument behind the Healthcare Brain, and the payer's implementation playbook for the federal medical prior authorization mandate.
WHITEPAPER · ARCHITECTURE · ~5,800 WORDS
Inside the Healthcare Brain.
The architecture powering production healthcare AI. Triple-Tier Agentic Architecture, six substrate principles, governance invariants, and the patent foundation behind production deployments.
Read the whitepaper WHITEPAPER · COMPLIANCE · ~5,400 WORDSMedical Prior Auth Compliance Engineering.
CMS-0057-F (in force) and the medical-PA components of CMS-0062-P (proposed). The payer's implementation playbook. FHIR PA APIs, decision timeframes, public reporting, no-auto-deny.
Read the whitepaper